What must be true for schedule II substances if the facility has less than 400 total dosage units?

For facilities that have less than 400 total dosage units of schedule II substances, the requirement is that these substances be kept in a locked cabinet. This requirement reflects the importance of maintaining security and preventing unauthorized access to controlled substances, which are considered to be at a higher risk for abuse and misuse.

Keeping schedule II drugs in a locked cabinet ensures that only authorized personnel can access these medications, safeguarding them against theft and potential diversion. Facilities with higher quantities may have different regulations based on the volume of controlled substances they handle, but those with fewer than 400 dosage units still must adhere to strict security measures to protect public health.

The other options do not align with the specific regulatory requirements for the storage of schedule II substances in facilities with less than 400 total dosage units. For instance, while keeping drugs in a safe may increase security, it is not a stringent requirement unless otherwise stated, and destruction is not appropriate unless the drugs are expired or no longer needed. Similarly, keeping substances behind the counter is not a standard requirement in this context, although it may provide some measure of security.